https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Role of cardiac computed tomography in hyperacute stroke assessment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54204 Wed 28 Feb 2024 15:18:26 AEDT ]]> The need for structured strategies to improve stroke care in a rural telestroke network in northern New South Wales, Australia: an observational study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45222 Wed 26 Oct 2022 15:50:17 AEDT ]]> Transient ischemic attack results in delayed brain atrophy and cognitive decline https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33724 Wed 24 May 2023 12:09:06 AEST ]]> Computed tomography perfusion identifies patients with stroke with impaired cardiac function https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37886 3 seconds and with clinical outcome measured using 3-month modified Rankin Scale. Results: A total of 732 ischemic stroke patients underwent computed tomography, 231 with transthoracic echocardiogram were included in part (1), 393 with outcome data were included in part (2). In part (1), 193/231 (83.5%) had normal LVEF (median 61%) and 38/231 (16.5%) decreased LVEF (median 39%). The low-LVEF group had significantly prolonged SO-EndAIF compared with normal-LVEF group (mean of 39.7 versus 26 second; P<0.001), and larger hypoperfusion lesions (94.9 versus 37.6 mL; P<0.001). SO-EndAIF time was strongly associated with EF, with an area under the curve of 0.86. Twenty nine seconds was the best threshold to distinguish between normal and impaired EF (area under the curve, 0.77). In part (2), the SO-EndAIF ≥29 second group had larger hypoperfusion volumes (21.8 versus 89.7 mL; P<0.001) and infarct core (12.2 versus 2.3 mL; P<0.0001) and patients with SO-EndAIF ≥29 seconds had fewer excellent or good clinical outcomes (modified Rankin Scale score 0–1; 40% versus 22%; OR, 2.79; P<0.001, modified Rankin Scale score 0–2; 65% versus 35%; OR, 1.41; P=0.033). Conclusions: AIF width correlates with ejection fraction in acute ischemic stroke. A 29-second threshold from scan onset to end of AIF accurately predicts reduced LVEF and identifies patients more likely to have worse outcomes after stroke.]]> Wed 17 Nov 2021 16:29:40 AEDT ]]> Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44396 Wed 12 Oct 2022 12:58:24 AEDT ]]> Transition in Incidence Rate of Hospitalised Stroke and Case Fatality Rate in the Hunter Region, Australia, 2001-2019: A Prospective Hospital-Based Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47020 Tue 13 Dec 2022 12:44:23 AEDT ]]> A model based on the Pennes bioheat transfer equation is valid in normal brain tissue but not brain tissue suffering focal ischaemia https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33726 Thu 28 Oct 2021 12:36:19 AEDT ]]> Air vs. road decision for endovascular clot retrieval in a rural telestroke network https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38503 Thu 18 Nov 2021 09:53:11 AEDT ]]> Growth hormone deficiency is frequent after recent stroke https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33725 Thu 13 Jan 2022 10:30:08 AEDT ]]> Ischemic Lesion Growth in Patients with a Persistent Target Mismatch After Large Vessel Occlusion https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47376  1.2, and mismatch volume > 10 mL on follow-up imaging. Patients were divided into PTM or non-PTM groups. Ischemic core and penumbral volumes were compared between baseline and follow-up imaging between the two groups, and collateral flow status assessed using CT perfusion collateral index. Results: A total of 25 patients (14 PTM and 11 non-PTM) were enrolled in the study. Median core volumes increased slightly in the PTM group, from 22 to 36 ml. There was a much greater increase in the non-PTM group, from 57 to 190 ml. Penumbral volumes were stable in the PTM group from a median of 79 ml at baseline to 88 ml at follow-up, whereas penumbra was reduced in the non-PTM group, from 120 to 0 ml. Collateral flow status was also better in the PTM group and the median collateral index was 33% compared with 44% in the non-PTM group (p = 0.043). Conclusion: Multiple patients were identified with limited core growth and large penumbra (persistent target mismatch) > 16 h after stroke onset, likely due to more favorable collateral flow.]]> Thu 06 Jul 2023 13:43:31 AEST ]]> MIDAS (Modafinil in Debilitating Fatigue after Stroke): a randomized, double-blind, placebo-controlled, cross-over trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33106 0.05). Conclusions: Stroke survivors with nonresolving fatigue reported reduced fatigue and improved quality of life after taking 200 mg daily treatment with modafinil.]]> Thu 03 Feb 2022 12:21:55 AEDT ]]> Modafinil treatment modulates functional connectivity in stroke survivors with severe fatigue https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35835 Thu 03 Feb 2022 12:21:17 AEDT ]]> Role of computed tomography perfusion in identification of acute lacunar stroke syndromes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38706 Mon 17 Jan 2022 15:59:07 AEDT ]]> Comparison of two pre-hospital stroke scales to detect large vessel occlusion strokes in Australia: A prospective observational study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46980 Mon 12 Dec 2022 17:01:27 AEDT ]]> No Evidence of the "Weekend Effect" in the Northern New South Wales Telestroke Network https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41805 Fri 12 Aug 2022 12:31:27 AEST ]]> Multimodal Computed Tomography Increases the Detection of Posterior Fossa Strokes Compared to Brain Non-contrast Computed Tomography https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41797 5 mL, the AUC was 0.87, 0.81, and 0.66, respectively. Conclusion: Comprehensive CTP analysis increases the detection of posterior fossa lesions compared to NCCT and should be implemented as part of the routine imaging assessment in posterior fossa strokes.]]> Fri 12 Aug 2022 12:24:26 AEST ]]>